Immuno Therapy for Cancer and Prevention : การเพิ่มภูมิคุ้มกันสำหรับผู้ที่เป็นมะเร็ง และสำหรับป้องกันให้แก่ผู้ที่มีความเสี่ยง
Numerous cancer cells form daily even in healthy individuals but when their immune system is working properly, their immune cells are able to detect and destroy them to keep the body healthy. However, today’s people who are exposed not only to genetic factors and stress but also carcinogens in the daily environmental often experience a breakdown in the sensitive balance between the immune system and cancer cells, and cancer cells that escape the attack of the immune cells continue to grow, resulting in masses and ultimately causing cancer in patients.
Tumors and surrounding tissues have been removed when possible through surgical procedures, and local radiation therapy and systemic chemotherapy have been administered, but this oftentimes results in recurrence or metastasis of the cancer in other organs. Cancer cells that are not completely eliminated through surgery, radiation or chemotherapy resurface and spread when the body’s immune system becomes weak.
Anti-cancer therapies using immune cells have been considered in order to solve the two problems of fundamental normalization of the immune system and systemic cancer therapy, but there have been many difficulties because of insufficiencies in culture technologies and activation of immune cells.
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However, anti-cancer immune cell therapy developed by Green Cross Cell collects immune cells from the patient’s own blood and amplifies several hundred folds, and therefore activates them as immune cells with strong anti-cancer properties and are re-injected to the patients. Immune cells that are amplified in number through the preparation process and activated to have strong anti cancer properties travel through the body to remove residual cancer cells to prevent recurrence.
Because our ant- cancer immune cell drug only uses immune cells of individual patients, it can enhance the quality of life of patients with virtually no pain or side effects.
Characteristics of Anti-Cancer Immune Cell Drug
• - It is effective in preventing recurrence and in removing residual cancer cells.
• - It causes almost no pain or side effects during treatment.
• - It can be accompanied by chemotherapy.
• - It improves the quality of the patient’s life.
The main groups that exhibit anti-cancer properties in anti-cancer immune cell drug are activated T lymphocytes and are composed of cytotoxic T lymphocytes and cytokine induced killer cells (CIK).
Among the immune cells present in our bodies are antigen-presenting cells that present antigens (virus, cancer, etc) to other immune cells. Antigen-presenting cells capture cancer cells and find out the protein information that is unique to the surface of the cancer cell. When this information is delivered to T lymphocytes, lymphocytes become activated (MHC class I Method) and become cytotoxic T lymphocytes. At this time, substances that promote other lymphocytes are released and activated to search for cancer cells.
Activated cytotoxic T lymphocytes use the information from antigen-presenting cells to identify cancer cells, and release enzymes that break the cancer cell surface causing them to rupture and die.
Cytokine induced killer cells (CIK) becomes capable, as stronger immune cells, of identifying and destroying cancer cells without antigen-presenting cells. Anti-cancer immune cell therapy comprised of these two cell groups supplement each other and can very effectively eliminate cancer.
We dyed cancer cells red and anticancer immune cells green to see how anticancer activity occurs. The green anticancer immune cells surround cancer cells and remove long cancer cells from the bottom, making them become round. Shortly, the cancer cells are found burst and dead, with substances inside the cancer cells pouring out.
Change in Cell Surface
The number of cells in the Anti-cancer immune cell drug that was prepared when the initial number of the cells from the patient was 30 million was 10 billion. Not only do they increase in quantity but because they are activated from their initial state of deactivated state and also converted to cytokine induced killer cells and cytotoxic T lymphocytes that have strong anti cancer properties, they are able to effectively locate and destroy cancer cells in patients, which in turn prevents recurrence and metastasis and ultimately improving the patients’ survival rate.